Hydrogen Ions Kill Brain at Concentrations Reached in Ischemia
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چکیده
منابع مشابه
Hydrogen ions kill brain at concentrations reached in ischemia.
Elevation of brain glucose before the onset of nearly complete ischemia leads to increased lactic acid within brain. When excessive, such acidosis may be a necessary factor for converting selective neuronal loss to brain infarction from nearly complete ischemia. To examine the potential neurotoxicity of excessive lactic acid concentrations, we microinjected (0.5 microliter/min) 150 mM sodium la...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 1987
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.1987.80